Spencer PN, Brown ME, Smith EP, Wang J, Kim W, Spiga L, Tasneem N, Simmons AJ, Kim T, Yang Y, Xu Y, Zheng L, Ro J, Kaur H, Kang SW, Helou MD, Lee MA, Arceneaux D, Mueller KD, Kuddar OS, Harned MH, Li J, Banerjee A, Markham NO, Wilson KT, Coburn LA, Goettel JA, Liu Q, Washington MK, Valdivia RH, Zhu W, Lau KS . Pathobiont-triggered induction of goblet cell response drives regional susceptibility to Inflammatory Bowel Disease. Journal of Clinical Investigation, online ahead of print.
Hoi XP, Stangis MM, Glass SE, Kim JH, Kang SW, Brennen WN, Li Z, Grady WM, Yegnasubramanian S, Kuhn P, Lyssiotis CA, Sagara A, Shrubsole MJ, Kadara H, Yuan Y, Coffey RJ, Lau KS , De Marzo AM, Maitra A, Min J, Yu M, Chan KS; TBEL Consortium. Cellular senescence in precancer lesions and early-stage cancers. Cancer Cell, 44(1):6-11, 2026.
Loberg MA, Xu GJ, Chen SC, Chen HC, Wahoski CC, Caroland KP, Tigue ML, Hartmann HA, Gallant JN, Phifer CJ, Ocampo AA, Wang DK, Fankhauser RG, Karunakaran KA, Wu CC, Tarabichi M, Shaddy SM, Netterville JL, Rohde SL, Solórzano CC, Bischoff LA, Baregamian N, Murphy BA, Choe JH, Wang JR, Huang EC, Sheng Q, Kagohara LT, Jaffee EM, Belcher RH, Lau KS , Ye F, Lee E, Weiss VL. An integrated single-cell and spatial transcriptomic atlas of thyroid cancer progression identifies prognostic fibroblast subpopulations. JCI Insight, 11(1):e191990, 2026.
Chen Z, Song W, Li Q, Li C, Wen W, Huyghe JR, Law PJ, Fernandez-Rozadilla C, Timofeeva MN, Thomas M, Schmit SL, Martin V, Devall M, Dampier C, Moratalla-Navarro F, Cai Q, Wang J, Shi J, Kweon SS, Tanikawa C, Jia WH, Shu X, Long J, Gao J, Kim J, Shin A, Matsuo K, Jee SH, Jung KJ, Wang N, Kim DH, Ping J, Yang G, Shin MH, Ren Z, Oh JH, Oze I, Ahn YO, Gao YT, Pan ZZ, Kamatani Y, Van Kaer L, Wu L, Li B, Matsuda K, Shu XO, Hsu L, Dunlop MG, Gruber SB, Houlston R, Tomlinson I, Li L, Lau KS , Moreno V, Casey G, Peters U, Zheng W, Guo X. Mixed-model and transcriptome-wide association analyses identify transcription factors and genes associated with colorectal cancer susceptibility. Nature Communications, 17(1):1377, 2026.
Liu Q, Wang Y, Hsu CY, Wanjalla CN, Lau KS , Shyr Y. Microenvironment-aware spatial modeling for accurate inference of cell identity. Nucleic Acids Research, 54(1):gkaf1477, 2026.
Li Q, Song Q, Chen Z, Choi J, Moreno V, Ping J, Wen W, Li C, Shu X, Yan J, Shu XO, Cai Q, Long J, Huyghe JR, Pai R, Gruber SB, Yang Y, Casey G, Wang X, Toriola AT, Li L, Singh B, Lau KS , Zhou L, Zhang Z, Wu C, Peters U, Zheng W, Long Q, Yin Z, Guo X. Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention. The American Journal of Human Genetics, 113(1):41-56, 2026.
Srinivasan J, Moore CR, Calindi A, Helm BR, Yang Y, Moore JF, Selden HJ, Heiser CN, Liu Q, Lau KS , Ehrlich LIR. The differentiation and function of heterogeneous thymic dendritic cell subsets require signals provided by distinct thymocyte cell types. Nature Immunology, 27(2):265-280, 2026.
Hu R, Wang Y, Yagan M, Xu Y, Simmons AJ, Lau KS , Liu Q, Gu G. Deregulated translation of the transcription factor Myt3 predisposes islet β-cells to dysfunction under obesity-induced metabolic stress. Journal of Biological Chemistry, 302(3):111164, 2026.
Ankenbauer KE, Yang Y, Chung CY, Andrade LR, Novak SW, Jarvis B, Ali Hanel WH, Liu J, Sarkisian V, Dani N, Krystofiak E, Hu G, Ebrahim S, Kachar B, Gong Q, Wahl GM, Lau KS , Brown JW, Manor U, DelGiorno KE. Protocadherin 20 Is a POU Class 2 Homeobox 3 Target Gene Required for Proper Tuft Cell Microvillus Organization. Cellular and Molecular Gastroenterology and Hepatology, online ahead of print.
Burman A, Brown ME, Yang Y, Momoh M, Adeniran F, Ramos C, Lau KS, Samuelson LC, Shub MD, Roland JT, Kaji I. Myosin VB is critical for progenitor cell identity and function in the intestine. Stem Cell Reportsonline ahead of print.