Heiser CN, Simmons AJ, Revetta F, McKinley ET, Ramirez-Solano MA, Wang J, Kaur H, Shao J, Ayers GD, Wang Y, Glass SE, Tasneem N, Chen Z, Qin Y, Kim W, Rolong A, Chen B, Vega PN, Drewes JL, Markham NO, Saleh N, Nikolos F, Vandekar SN, Jones AL, Washington MK, Roland JT, Chan KS, Schuerpf T, Sears CL, Liu Q, Shrubsole MJ, Coffey RJ*, Lau KS*. Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors. Cell, 186(25): 5620-5637, 2023. * Corresponding Authors
Bao S, Cui C, Li J, Tang Y, Lee HH, Deng R, Remedios LW, Yu X, Yang Q, Chiron S, Patterson NH, Lau KS , Liu Q, Roland JT, Coburn LA, Wilson KT, Landman BA, Huo Y. Topological-Preserving Membrane Skeleton Segmentation in Multiplex Immunofluorescence Imaging. Proceedings of Society of Photo-Optical Instrumentation Engineers, 12471:124710B, 2023.
Arceneaux D, Chen Z, Simmons AJ, Heiser CN, Southard-Smith AN, Brenan MJ, Yang Y, Chen B, Xu Y, Choi E, Campbell JD, Liu Q, Lau KS. A contamination focused approach for optimizing the single-cell RNA-seq experiment. iScience, 26(7):107242, 2023.
Remedios LW, Bao S, Kerley CI, Cai LY, Rheault F, Deng R, Cui C, Chiron S, Lau KS, Roland JT, Washington MK, Coburn LA, Wilson KT, Huo Y, Landman BA. Predicting Crohn’s disease severity in the colon using mixed cell nucleus density from pseudo labels. Proceedings of Society of Photo-Optical Instrumentation Engineers, 12471:1247116, 2023.
Shui B, Beyett TS, Chen Z, Li X, La Rocca G, Gazlay WM, Eck MJ, Lau KS , Ventura A, Haigis KM. Oncogenic K-Ras suppresses global miRNA function. Molecular Cell, 83(14):2509-2523, 2023.
Cui C, Bao S, Li J, Deng R, Remedios LW, Asad Z, Chiron S, Lau KS , Wang Y, Coburn LA, Wilson KT, Roland JT, Landman BA, Liu Q, Huo Y. Influence of Cell-type Ratio on Spatially Resolved Single-cell Transcriptomes using the Tangram Algorithm: Based on Implementation on Single-Cell and MxIF Data. Proceedings of Society of Photo-Optical Instrumentation Engineers, 12471:124710A, 2023.
Zilbauer M, James KR, Kaur M, Pott S, Li Z, Burger A, Thiagarajah JR, Burclaff J, Jahnsen FL, Perrone F, Ross AD, Matteoli G, Stakenborg N, Sujino T, Moor A, Bartolome-Casado R, Bækkevold ES, Zhou R, Xie B, Lau KS , Din S, Magness ST, Yao Q, Beyaz S, Arends M, Denadai-Souza A, Coburn LA, Gaublomme JT, Baldock R, Papatheodorou I, Ordovas-Montanes J, Boeckxstaens G, Hupalowska A, Teichmann SA, Regev A, Xavier RJ, Simmons A, Snyder MP, Wilson KT; Gut Cell Atlas Consortium; Human Cell Atlas Gut Biological Network Consortium. A Roadmap for the Human Gut Cell Atlas. Nature Reviews Gastroenterology and Hepatology, 20(9):597-614, 2023.
Chen Z, Lau KS . Advances in Mapping Tumor Progression from Precancer Atlases. Cancer Prevention Research, 16(8):439-447, 2023.
Pilat JM, Brown RE, Chen Z, Berle NJ, Othon AP, Washington M, Anant SA, Kurokawa S, Ng VH, Thompson JJ, Jacobse J, Goettel JA, Lee E, Choksi YA, Lau KS , Short SP, Williams CS. SELENOP modifies sporadic colorectal carcinogenesis and WNT signaling activity through LRP5/6 interactions. Journal of Clinical Investigation, 133(13):e165988, 2023.
Jacobse J, Brown RE, Li J, Pilat JM, Pham L, Short SP, Peek CT, Rolong A, Washington MK, Martinez-Barricarte R, Byndloss MX, Shelton C, Markle JG, Latour YL, Allaman MM, Cassat JE, Wilson KT, Choksi YA, Williams CS, Lau KS , Flynn CR, Casanova JL, Rings EHHM, Samsom JN, Goettel JA. Interleukin-23 receptor signaling impairs the stability and function of colonic regulatory T cells. Cell Reports, 42(2):112128, 2023.
Lin JR, Wang S, Coy S, Chen YA, Yapp C, Tyler M, Nariya MK, Heiser CN, Lau KS , Santagata S, Sorger PK. Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer. Cell, 186(2):363-38, 2023.
Taufalele PV, Wang W, Simmons AJ, Southard-Smith AN, Chen B, Greenlee JD, King MR, Lau KS, Hassane DC, Bordeleau F, Reinhart-King CA. Matrix stiffness enhances cancer-macrophage interactions and M2-like macrophage accumulation in the breast tumor microenvironment. Acta Biomaterialia, 163: 365-377, 2023.
Cui C, Wang Y, Bao S, Tang Y, Deng R, Remedios LW, Asad Z, Roland JT, Lau KS , Liu Q, Coburn LA, Wilson KT, Landman BA, Huo Y. Feasibility of Universal Anomaly Detection without Knowing the Abnormality in Medical Images. Medical Image Learning with Limited and Noisy Data, 14307:82-92, 2023.